ErbB2 plays an important role in human malignancies. The erbB2 gene is amplified or overexpressed in approximately 30% of human breast cancers and in.
HER2-positive breast cancers tend to be more aggressive compared to other types of breast cancer. They're also less responsive to hormone.
In breast tumors, ErbB2 overexpression is detected in up to 20% of patients. Breast cancers in with amplification of ErbB2 are characterized by.
It is strongly associated with increased disease recurrence and a poor prognosis; however, drug agents targeting HER2 in breast cancer.